Hi Vinatha,
Please take a look at this code sample here, which demonstrates client-side communications between Asp.net application and a Visual WebGui application.
Regarding different versions of Visual Studio used for developing your asp.net and Visual WebGui application, then you would be able to accomplish that client-side, as you can see in the sample, provided that you add the relevant javascript on both sides. You will however have problems during development, as your VS2008 project would need to reference an assembly built for higher version of .NET than it supports. VS2008 supports .NET 2.0 up to 3.5, but VS2010 by default builds in .NET 4.0. Although I have not tested, it is possible that you would be able to make this work, but then you would have to set VS2010's target framework to NET3.5, and that would require you to manually obtain Visual WebGui NET3.5 assemblies and set your VS2010 environment to use NET3.5 instead of NET4.0.
Palli